鈴木 康夫 SUZUKI Yasuo
プロフィール
著書および訳書
糖鎖を知る その素顔と病気への挑戦 (共著)科学技術新興機構, 2010
インフルエンザ21世紀(監修)文春新書, 文芸春秋社, 2009
インフルエンザの感受性は糖鎖で決まる。第3の生命鎖、糖鎖の謎が今、解る(文部科学省 特定領域研究 糖鎖によるタンパク質と分子複合体の機能調節)(共著), クバプロ, 2009
糖鎖科学総論:化学からシステム生物学へ(英文、共著)エルセビア, 2007
糖鎖科学の新展開―その合成法と医療応用のすべて―(共著)(株)エヌ・ティー・エス, 2005
キャンベル・ファーレル 生化学 (共翻訳)廣川書店, 2004
コールドスプリングハーバー糖鎖生物学(鑑翻訳)丸善, 2003
茶の機能(共著)学会出版センター, 2001
医薬科ウイルス学(共著)医薬ジャーナル社, 1998
ガングリオシド研究法I, II(編著)学会出版センター, 1995
学術論文、評論
Antiplasmodial effects of Brucea javanica (L.) Merr. and Eurycoma longifolia Jack extracts and their combination with chloroquine and quinine on Plasmodium falciparum in culture. Tropical Medicine and Health 38 (2) in press (2010)
Emergence of H5N1 Avian Influenza Viruses with Reduced Sensitivity to Neuraminidase Inhibitors and Novel Reassortants in LAO PDR. J. gen Virol., 91, 949-959 (2010)
Alterations in receptor binding properties of swine influenza viruses of H1 subtype after isolation in embryonated chicken eggs. J. gen. Virol., 91, 938-948 (2010)
Identification of amino acid residues of influenza A virus H3 HA containing to the recognition of molecular species of sialic acid. FEBS Lett. 583 (19) 3171-3174 (2009)
Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities. Virology Journal, 6, 124 Open access, doi:10.1186/1743-422X-6-124 (2009)
Syntheses and biological evaluations of carbosilane dendrimers uniformly functionalized with sialyl α(2→3) lactose moieties as inhibitors for human influenza viruses. Bioorganic & Medicinal Chemistry, 17, 5465-5475 (2009)
Systematic synthesis of influenza neuraminidase inhibitors: A series of carbosilane dendorimers uniformly functionalized with thioglycoside-type sialic acid moieties. Bioorgnanic & Medicinal Chemistry, 17, 5451-5464 (2009)
Synthesis of sialic acid derivatives having a C=C double bond substituted at the C-5 position and their glycopolymers. Bioorg.& Biomed. Chem. Lett., 19, 5105-5108 (2009)
The Highly Pathogenic Avian Influenza H5N1 - Initial Molecular Signals for Next influenza Pandemic-. Chang Gung Med. J., 32, 258-263 (2009)
Determination of N-linked sialyl-sugar chains in the lungs of domestic cats and dogs in Thailand susceptible to the highly pathogenic avian influenza virus (H5N1). Open Glycoscience, 2, 28-36 (2009)
Analysis of N-glycans in embryonated chicken egg chorioallantoic and amniotic cells responsible for binding and adaptation of influenza viruses. Glycoconjugate J., 26, 433-443 (2009)
Ab initio base fragment molecular orbital studies of influenza viral hemagglutinin HA1 full-domains in complex with sialoside receptors. J. Mol. Genet. Med., 3, 133-142 (2009)
Limited inhibitory effects of Oseltamivir and Zanamivir on Human sialidases. Antimicrobial Agents and Chemotherapy 52, 3467-3471 (2008)
Sulfatide regulates influenza A virus replication by association with hemagglutinin delivered to the cell surface. J. Virol., 82 (12) 5940-5950 (2008)
Clarithromycin inhibits progeny virus production from influenza virus – Infected host cells. Biol. Pharm. Bull. Vol. 31, 2008
The quail and chicken have sialyl-Gal sugar chains responsible for the binding of influenza A viruses to human type receptors. Glycobiology Vol. 17, 713-724 (2007)
Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity. Bioorg. Med. Chem. Lett., Vol. 17, 2007
An avian influenza H5N1 virus that binds to a human-type receptor. J. Virol., Vol. 81, 2007
Hemagglutinin nutations responsible for the binding of H5N1 influenza A viruses to human-type receptors Nature, Vol. 444, 2006
Edible bird's nest extract inhibits influenza virus infection. Antiviral Res., Vol. 70, 2006
Identification and characterization of carbohydrate molecules in mammalian cells recognized dengue virus type 2. J. Biochem., Vol. 139, 2006
Isolation of drug-resistant H5N1 virus. Nature, Vol. 437, 2005
Sialidase activity of influenza A virus in an endocytic pathway enhances viral replication. J. Virol. Vol. 79, 2005
Characterization of a Human H5N1 Influenza A Virus Isolated in 2003. J. Virol. Vol. 79, 2005
The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 human immunodeficiency virus type 1. J. Biol. Chem., Vol. 280, 2005
Influence of glycosylation on the efficacy of an Env-based vaccine against SIVmac239 in a macaque AIDS model. J. Virol. Vol.79, 2005
Sialobiology of influenza -Molecular Mechanism of Host Range Variation of Influenza Viruses- (Review). Biological Phamaceutical Bulletin Vol. 28, 2005
Enhanced pathogenicity of influenza A viruses possessing the haemagglutinin of the 1918 pandemic. Nature, Vol. 431, 2004
Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstruction. J. Biol. Chem., Vol. 279, 2004
Glycotentacles:Synthesis of cyclic glycopeptides toward a tailored blocker of influenza virus hemagglutinin. Angew. Chem. Int. Ed., Vol. 42, 2003
フィールドワーク、作品
糖鎖ウイルス学情報交換サイトの開設
http://www.glycoforum.gr.jp/index.html 10月12日, 2007
受賞
日本薬学会賞(平成16年度)
中日文化賞(平成16年度)
社会活動
日本糖質学会副会長
日本糖鎖科学コンソーシアム理事
グリフィス大学(オーストラリア)客員教授
浙江省医学科学院(中国)客員教授