高橋 広夫 TAKAHASHI Hiro
プロフィール
| 生年 | 1978 |
|---|---|
| 出身 | 広島県広島市 |
| 職名 | 講師 |
| 所属 |
応用生物学部 応用生物化学科 大学院 応用生物学研究科 応用生物学専攻 |
| 最終学歴 | 名古屋大学大学院工学研究科 |
| 学位 | 博士(工学)(名古屋大学) |
| 所属学会・役職 | 化学工学会会員 日本バイオインフォマティクス学会会員 日本生物工学会会員 日本癌学会会員 バイオインダストリー協会会員 情報計算化学生物学会会員 |
| 専門分野 | バイオインフォマティクス、バイオテクノロジー |
| 研究テーマ | 遺伝子情報からの治療・診断マーカー探索、ヒト多型情報を用いた薬剤応答予測、ペプチドインフォマティクス、遺伝子ネットワーク解析
|
| 授業科目 | バイオインフォマティクス、推計学入門、基礎物理学、生物情報リテラシー |
| 共同研究キーワード | バイオインフォマティクス |
著書および訳書
バイオプロダクション（共著）, コロナ社, 2006
Focus on Genetic Screening Research（共著）, NOVA Science Publishers, Inc., 2006
学術論文、評論
Identification of alternative splicing events regulated by an Arabidopsis serine/arginine-like protein, atSR45a, in response to high-light stress using a tiling array. Plant Cell Physiol., 52(10), 1786-1805, 2011
ASYMMETRIC LEAVES2 and Elongator, a Histone Acetyltransferase Complex, Mediate the Establishment of Polarity in Leaves of Arabidopsis thaliana. Plant Cell Physiol., 52(8), 1259-1273, 2011
Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis. Int. J. Oncol., 36(2), 321-330, 2010
Identification of ENHANCER OF SHOOT REGENERATION 1-upregulated genes during in vitro shoot regeneration Plant Biotechnol., 26(4), 385-393, 2009
Knowledge-based Fuzzy Adaptive Resonance Theory and its Application to the Analysis of Gene Expression in Plants. J.Biosci. Bioeng. 106(6), 587-593, 2008
Proposal of newly gene filtering method, BagPART, for gene expression analysis with small samples., J.Biosci. Bioeng. 105(1), 81-84, 2008
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma., Mod. Pathol., 20(7), 749-759, 2007.
New cancer diagnosis modeling using boosting and projective adaptive resonance theory with improved reliable index, Biochem. Eng. J., 33(2), 100-109, 2007
Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive resonance theory (PART) filtering method, BMC Bioinformatics, 7:399, 2006
Classification of intramural metastases and lymph node metastases of esophageal cancer from gene expression based on boosting and projective adaptive resonance theory, J.Biosci. Bioeng. 102(1), 46-52, 2006
Lymphoma prognostication from expression profiling using a combination method of boosting and projective adaptive resonance theory, J. Chem. Eng. Jpn., 39(7), 767-771, 2006
Modified signal-to-noise: a new simple and practical gene filtering approach based on the concept of projective adaptive resonance theory (PART) filtering method, Bioinformatics, 22(13), 1662-1664, 2006
Prediction of peptide binding to major histocompatibility complex class II molecules through use of boosted fuzzy classifier with SWEEP operator method, J.Biosci.Bioeng., 101(2),137-141, 2006
A new reliable cancer diagnosis method using boosted fuzzy classifier with SWEEP operator method, J. Chem. Eng. Jpn., 38(9), 763-773, 2005
Construction of robust prognostic predictors by using projective adaptive resonance theory as a gene filtering method, Bioinformatics, 21(2), 179-186, 2005
Prognostic predictor with multiple fuzzy neural models using expression profiles from DNA microarray for metastases of breast cancer, J.Biosci.Bioeng., 98(3),193-199, 2004
Inference of common genetic network using fuzzy adaptive resonance theory associated matrix method, J.Biosci.Bioeng., 96(2),154-160, 2003
受賞
The 80th Annual Meeting of Genetics Society of Japan Best Paper Award 2008 Machida C., Iwakawa H., Takahashi H., Mazet Rémi, Iwasaki M., Kojima S., Kobayashi T. and Machida Y. : Analysis of genetic network of gene regulation mediated by AS2 and AS1 in the leaf development in Arabidopsis thaliana September 2009 (Nagoya)
