中部大学

中部大学

教員情報

堂前 純子 ABE-DOHMAE Sumiko

プロフィール

職名 教授
所属 応用生物学部 食品栄養科学科
管理栄養実習センター
大学院 応用生物学研究科 応用生物学専攻
最終学歴 名古屋市立大学大学院医学研究科・生理系専攻・博士課程修了
学位 医学博士(名古屋市立大学)
資格 医師
所属学会・役職 日本生化学会
日本動脈硬化学会
日本脂質生化学会
専門分野 生化学
研究テーマ コレステロールホメオスタシスと細胞機能
授業科目 健康管理概論、臨床栄養学総論、臨床医科学Ⅰ・II

学術論文、評論

Isobe-Sasaki Y, Fukuda M, Ogiyama Y, Sato R, Miura T, Fuwa D, Mizuno M, Matsuoka T, Shibata H, Ito H, Ono M, Abe-Dohmae S, Kiyono K, Yamamoto Y, Kobori H, Michikawa M, Hayano J, Ohte N. Sodium balance, circadian BP rhythm, heart rate variability, and intrarenal renin-angiotensin-aldosterone and dopaminergic systems in acute phase of ARB therapy. Physiol Rep. 2017 Jun; 5: e13309.

Fuwa D, Fukuda M, Ogiyama Y, Sato R, Mizuno M, Miura T, Abe-Dohmae S, Michikawa M, Kobori H, Ohte N. Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease. J Renin Angiotensin Aldosterone Syst. 2016 17:1470320316652032.

Satoh K, Abe-Dohmae S, Yokoyama S, St George-Hyslop P, Fraser PE. ATP-binding Cassette Transporter A7 (ABCA7) Loss of Function Alters Alzheimer Amyloid Processing. J Biol Chem. 2015 290:24152-65.

Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S. Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum. J Biol Chem. 2015 290:23464-77.

Hotta N, Abe-Dohmae S, Taguchi R, Yokoyama S. Preferential Incorporation of Shorter and Less Unsaturated Acyl Phospholipids into High Density Lipoprotein-Like Particles in the ABCA1- and ABCA7-mediated Biogenesis with apoA-I. Chem Phys Lipids. 2015 187:1-9.

Abe-Dohmae S, Yokoyama S. ABCA7, a potential mediator between cholesterol homeostasis and host defense system. Clinical Lipidology 2012 7: 677-687

Ito J, Nagayasu Y, Kheirollah A, Abe-Dohmae S, Yokoyama S. ApoA-I enhances generation of HDL-like lipoproteins through interaction between ABCA1 and phospholipase Cγ in rat astrocytes. Biochim Biophys Acta. 2011 1811:1062-1069.

Jayaraman S, Abe-Dohmae S, Yokoyama S, Cavigiolio G. Impact of self-association on function of apolipoprotein A-I. J Biol Chem. 2011 286:35610-35623.

Yokoyama S, Arakawa R, Wu CA, Iwamoto N, Lu R, Tsujita M, Abe-Dohmae S. Calpain-mediated ABCA1 degradation: Post-translational regulation of ABCA1 for HDL biogenesis. Biochim Biophys Acta. 2012 1821:547-51.

Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7. Atherosclerosis. 2011 217:407-414.

Nonomura K, Arai Y, Mitani H, Abe-Dohmae S, Yokoyama S. Insulin down-regulates specific activity of ATP-binding cassette transporter A1 for high density lipoprotein biogenesis through its specific phosphorylation. Atherosclerosis. 2011 216:334-341.

Tanaka N, Abe-Dohmae S, Iwamoto N, Yokoyama S. Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System. J Atheroscler Thromb. 2011 18:274-281.

Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7. J Lipid Res. 2010 51:2591-2599.

Iwamoto N, Lu R, Tanaka N, Abe-Dohmae S, Yokoyama S. Calmodulin Interacts With ATP Binding Cassette Transporter A1 to Protect From Calpain-Mediated Degradation and Upregulates High-Density Lipoprotein Generation. Arterioscler Thromb Vasc Biol. 2010 30:1446-1452.

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