CHUBU UNIVERSITY
  • Print only the body of the page. Set to print background colors and images.
  • Print the whole page. Set to print background colors and images.

MATSUMOTO Yoshihiro

Profile

Year of Birth 1957
Place of Birth Kyoto
Title Professor
Belong to College of Bioscience and Biotechnology
Bioscience and Biotechnology (graduate school)
Graduated Kyoto University Graduate School of Science
Degree Doctor of Science, Kyoto University
Field of Study Molecular Biology
Research, Studies Coordination of DNA replication and repair, Mechanism of anti-cancer drugs
Contact Mail address:ymatsumoto@isc.chubu.ac.jp

Academic Papers, Critique

Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst).60:29-39, 2017.

Hammel M, Yu Y, Radhakrishnan SK, Chokshi C, Tsai MS, Matsumoto Y, Kuzdovich M, Remesh SG, Fang S, Tomkinson AE, Lees-Miller SP, Tainer JA. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex. J Biol Chem. 291:26987-27006, 2016.

Peng Z, Liao Z, Matsumoto Y, Yang A, Tomkinson AE. Human DNA Ligase I Interacts with and is Targeted for Degradation by the DCAF7 Specificity Factor of the CUL4-DDB1 Ubiquitin Ligase Complex. J Biol Chem 291:21893-21902, 2016.

Sallmyr A, Matsumoto Y, Roginskaya V, Van Houten B, Tomkinson AE. Inhibiting Mitochondrial DNA Ligase III╬▒ Activates Caspase 1-Dependent Apoptosis in Cancer Cells. Cancer Res. 76:5431-41, 2016.

Greco GE, Matsumoto Y, Brooks RC, Lu Z, Lieber MR, Tomkinson AE. SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV. DNA Repair (Amst). 43:18-23, 2016.

Matsumoto Y, Rodriguez V, Whitford TA, Beeharry N, Ide H, Tomkinson AE. Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells. Oncoscience. 2:272-84, 2015.

Yang H, Matsumoto Y, Trujillo KM, Lees-Miller SP, Osley MA, Tomkinson AE. Role of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joining. DNA Repair. 31:1-10, 2015.

Gamper AM, Choi S, Matsumoto Y, Banerjee D, Tomkinson AE, Bakkenist CJ. ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis. J. Biol. Chem. 287:12445-54, 2012.

Peng Z, Liao Z, Dziegielewska B, Matsumoto Y, Thomas S, Wan Y, Yang A, Tomkinson AE. Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair. J. Biol. Chem. 287:36711-9, 2012.

Della-Maria J, Hegde ML, McNeill DR, Matsumoto Y, Tsai MS, Ellenberger T, Wilson DM 3rd, Mitra S, Tomkinson AE. The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites. J. Biol. Chem. 287:39233-44, 2012.

Cortellino S, Xu, J., Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wessels A, Soprano D, Abramowitz LK, Bartolomei MS, Rambow F, Bassi MR, Bruno T, Fanciulli M, Renner C, Klein-Szanto AJ, Matsumoto Y, Kobi D, Davidson I, Alberti C, Larue L, Bellacosa A. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell. 146:67-79, 2011.

Fazlieva R, Spittle CS, Morrissey D, Hayashi H, Yan H, Matsumoto Y. Proofreading exonuclease activity of human DNA polymerase and its effects on lesion-bypass DNA synthesis. Nucleic Acids Res. 37:2854-66, 2009.

Page Top