研究テーマ
金属触媒的新規基質支配反応の開発
略歴
| 2013年3月 | 岐阜薬科大学薬学部薬学科 卒業 |
| 2017年3月 | 岐阜薬科大学大学院薬学研究科博士課程 修了 博士（薬学） |
職歴
| 2015年4月 | 日本学術振興会特別研究員（DC2） |
| 2017年4月 | 中部大学分子性触媒研究センター 特任助教（山本尚教授） |
| 2020年4月 | 中部大学先端研究センター 特任講師（山本尚教授） |
| 2023年4月 | 中部大学先端研究センター 特任准教授（山本尚教授） |
Objective
Metal Catalyzed Substrate-Controlled Reactions
Degree
| 2013 | B.Pharm Sc. Gifu Pharmaceutical University, Gifu, Japan |
| 2017 | Ph.D. Gifu Pharmaceutical University, Gifu, Japan (Pharmacy) |
Experience
| 2015-2017 | Research Fellow of the Japan Society for the Promotion of Science (DC2) |
| 2017-2020 | Research Assistant professsor Chubu University (Japan) PI: Prof. Hisashi Yamamoto |
| 2020-2023 | Senior assistant professor Chubu University (Japan) PI: Prof. Hisashi Yamamoto |
| 2023- | Associate professor Chubu University (Japan) PI: Prof. Hisashi Yamamoto |
List of Publications and Awards
25. Peptide Bond Formation Between Unprotected Amino Acids: Convergent Synthesis of Oligopeptides.
T. Hattori, H. Yamamoto, J. Am. Chem. Soc., 2024, 146, 25738-25744.
24. Triisobutylaluminium-Mediated Regioselective Protection of Sterically Hindered Amide NH of Cyclo-(AA-Gly): Key Building Block for Next-Generation Peptide Synthesis.
I. Ramakrishna, T. Hattori, H. Yamamoto, Synlett, 2024, 35, 1113-1120.
23. 令和５年度有機合成化学協会奨励賞
22. Trimethylaluminum-mediated one-pot peptide elongation.
T. Hattori, H. Yamamoto, Chem. Sci., 2023, 14, 5795-5801.
21. Thieme Chemistry Journals Award 2023.
20. Silicon-based hydrophobic tags applied in liquid-phase peptide synthesis: protected DRGN-1 and poly alanine chain synthesis.
A. Wu, I. Ramakrishna, T. Hattori, H. Yamamoto, Org. Biomol. Chem., 2022, 20, 8685-8692.
19. Synthesis of Silacyclic Dipeptides: Peptide Elongation at Both N- and C-Termini of Dipeptide.
T. Hattori, H. Yamamoto, J. Am. Chem. Soc. 2022, 144, 1758-1765.
18.Amide bond formation: beyond the dilemma between activation and racemisation.
W. Muramatsu, T. Hattori, H. Yamamot, Chem. Commun.. 2021, 57, 6346-6359.
17. Regio- and Stereoselective (SN2) N-, O-, C- and S-Alkylation using Trialkyl Phosphates.
A. Banerjee, T. Hattori, H. Yamamoto, Synthesis, 2023, 55, 315-332.
16. 基質支配的アミド結合形成反応：ペプチド合成の新機軸.
服部倫弘, 村松渉, 山本尚, 有機合成化学協会誌, 2021, 79, 382-390
15. Game Change from Reagent- to Substrate-Controlled Peptides Synthesis.
W. Muramatsu, T. Hattori, H. Yamamoto, Bull. Chem. Soc. J., 2020, 93, 759-767.
14. Substrate-Directed Lewis-Acid Catalysis for Peptide Synthesis.
W. Muramatsu, T. Hattori, H. Yamamoto, J. Am. Chem. Soc., 2019, 141, 12288-12295.
13. Selective Synthesis of Primary Amines from Nitriles under Hydrogenation Conditions.
M. Yoshimura, A. Komatsu, M. Niimura, Y. Takagi, T. Takahashi, S. Ueda, T. Ichikawa, Y. Kobayashi, H. Okami, T. Hattori, Y. Sawama, Y. Monguchi, H. Sajiki, Adv. Synth. Catal., 2018, 360, 1726-1732.
12. ニッケルを触媒とした臭化アルキル化合物の遠隔位カルボキシル化反応
服部倫弘, ファルマシア, 2018, 54, 351.
11. Catalyst-Dependent Selective Hydrogenation of Nitriles: Selective Synthesis of Tertiary and Secondary Amines.
Y. Monguchi, M. Mizuno, T. Ichikawa, Y, Fujita, E. Murakami, T. Hattori, T. Maegawa, Y. Sawama, H. Sajiki, J. Org. Chem. 2017, 82, 10939-10944.
10. Ruthenium on carbon catalysed carbon-carbon cleavage of aryl alkyl ketones and aliphatic aldehydes in aqueous media.
T. Hattori, H. Okami, T. Ichikawa, S. Mori, Y. Sawama, Y. Monguchi, H. Sajiki, Adv. Synth. Catal. 2017, 359, 3490-3495.
9. Heterogeneous one-pot carbonylation and Mizoroki–Heck reactions in a parallel manner following the cleavage of cinnamaldehyde derivatives.
T. Hattori, S. Ueda, R. Takakura, Y. Sawama, Y. Monguchi, H. Sajiki, Chem. Eur. J. 2017, 23, 8196-8202; Selected to be highlighted on the ChemistryViews website
8. Palladium-Catalyzed C-H Monoalkoxylation of α,β-Unsaturated Carbonyl Compounds.
Y. Monguchi, K. Kunishima, T. Hattori, T. Takahashi, Y. Shishido, Y. Sawama, H. Sajiki, ACS Catalysis 2016, 6, 3994–3997.
7. Switching the Cleavage Sites in Palladium on Carbon-Catalyzed Carbon-Carbon Bond Disconnection.
T. Hattori, R. Takakura, T. Ichikawa, Y. Sawama, Y. Monguchi, H. Sajiki, J. Org. Chem. 2016, 81, 2737–2743; Highlighted in Synfacts 2016, 753.
6. Tertiary-Amino-Functionalized Resin-Supported Palladium Catalyst for the Heterogeneous Suzuki-Miyaura Reaction of Aryl Chlorides
Y. Monguchi, T. Ichikawa, M. Netsu, T. Hattori, T. Mizusaki, Y. Sawama, H. Sajiki, Synlett 2015, 26, 2014–2018.
5. Facile Arene Hydrogenation under Flow Conditions Catalyzed by Rhodium or Ruthenium on Carbon.
T. Hattori, T. Ida, A. Tsubone, Y. Sawama, Y. Monguchi, H. Sajiki, Eur. J. Org. Chem. 2015, 11, 2492–2497.
4. Palladium on Carbon-Catalyzed Suzuki-Miyaura Coupling Reaction Using an Efficient and Continuous Flow System.
T. Hattori, A. Tsubone, Y. Sawama, Y. Monguchi, H. Sajiki, Catalysts 2015, 5, 18–25.
3. Systematic evaluation of the palladium-catalyzed hydrogenation under flow conditions.
T. Hattori, A. Tsubone, Y. Sawama, Y. Monguchi, H. Sajiki, Tetrahedron 2014, 70, 4790–4798; Highlighted in Synfacts 2014, 992.
2. Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon.
H. Esaki, T. Hattori, A. Tsubone, S. Mibayashi, T. Sakata, Y. Sawama, Y. Monguchi, H. Yasuda, K. Nosaka, H. Sajiki, ChemCatChem 2013, 13, 3629–3635.
1. Palladium on Carbon-Catalyzed Cross-Coupling Using Triarylbismuths.
Y. Monguchi, T. Hattori, Y. Miyamoto, T. Yanase, Y. Sawama, H. Sajiki, Adv. Synth. Catal. 2012, 354, 2561–2567.
Patent
11. アミド反応用用反応剤及びそれを用いたアミド化合物の製造方法、国際公開番号WO/2021/085635
10. アミド反応用用反応剤及びそれを用いたアミド化合物の製造方法、国際公開番号WO/2021/085636
9. アミド化合物の製造方法、国際公開番号WO/2021/085636
8. アミド化合物の製造方法、国際公開番号WO/2021/208731
7. アミド化合物の製造方法、国際公開番号WO/2021/199147
6. 不均一系パラジウム触媒存在下でアルデヒドを一酸化炭素源として用いるハロゲン化合物のカルボニル化反応によりカルボニル化合物を得る方法ビフェニル化合物の合成法、特許第6871802号
5. フェノール誘導体の選択的メチル化方法、特許第6871793号
4. 白金族金属担持触媒及び反応装置、特許第6042278号
3. 白金族担持型接触水素化還元触媒及び水素化還元方法、特許第6042277号
2. ビフェニル化合物の合成法、特許第5907006号
1. ビフェニル化合物の合成法、特許第5907005号