中部大学実験動物教育研究センターの主な研究成果
2024年
A Recql5 mutant facilitates complex CRISPR/Cas9-mediated chromosomal engineering in mouse zygotes.
Iwata, S., Nagahara, M., Ido, R., & Iwamoto, T.
Genetics, 2024, 227(2), iyae054.
2021年
An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain.
Iwata, S., Sasaki, T., Nagahara, M., & Iwamoto, T.
G3: Genes, Genomes, Genetics, 2021, 11(8), jkab194.
2020年
Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift.
Ogawa, K., Noda, A., Ueda, J., Ogata, T., Matsuyama, R., Nishizawa, Y., Qiao, S., Iwata, S., Ito, M., Fujihara, Y., Ichihara, M., Adachi, K., Takaoka, Y., Iwamoto, T.
Cellular & molecular biology letters, 2020, 25: 40-40
2019年
Simple and large-scale chromosomal engineering of mouse zygotes via in vitro and in vivo electroporation.
Iwata, S., Nakadai, H., Fukushi, D., Jose, M., Nagahara, M., & Iwamoto, T.
Scientific reports, 2019, 9.1: 1-8.doi: https://doi.org/10.1038/s41598-019-50900-y
2017年
Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis.
Ueda J, Harada A, Urahama T, Machida S, Maehara K, Hada M, Makino Y, Nogami J, Horikoshi N, Osakabe A, Taguchi H, Tanaka H, Tachiwana H, Yao T, Yamada M, Iwamoto T, Isotani A, Ikawa M, Tachibana T, Okada Y, Kimura H, Ohkawa Y, Kurumizaka H, Yamagata K.
Cell Rep. 2017 Jan 17;18(3):593-600. doi: 10.1016/j.celrep.2016.12.065.
PMID: 28099840
2013年
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2.
Ouchi Y, Banno Y, Shimizu Y, Ando S, Hasegawa H, Adachi K, Iwamoto T.
J Neurosci. 2013 May 29;33(22):9408-19. doi: 10.1523/JNEUROSCI.2700-12.2013.
PMID: 23719809